A Transparent, Wearable Fluorescent Mouthguard for High-Sensitive Visualization and Accurate Localization of Hidden Dental Lesion Sites.
Identifieur interne : 000051 ( Main/Exploration ); précédent : 000050; suivant : 000052A Transparent, Wearable Fluorescent Mouthguard for High-Sensitive Visualization and Accurate Localization of Hidden Dental Lesion Sites.
Auteurs : Xuemeng Li [République populaire de Chine] ; Chongdai Luo [République populaire de Chine] ; Quanying Fu [République populaire de Chine] ; Cuiping Zhou [République populaire de Chine, États-Unis] ; Marina Ruelas [États-Unis] ; Yingshuting Wang [République populaire de Chine] ; Jinxu He [République populaire de Chine] ; Yangyang Wang [République populaire de Chine] ; Yu Shrike Zhang [États-Unis] ; Jianhua Zhou [République populaire de Chine, États-Unis]Source :
- Advanced materials (Deerfield Beach, Fla.) [ 1521-4095 ] ; 2020.
Descripteurs français
- KwdFr :
- Composés du soufre (analyse), Composés du soufre (composition chimique), Composés du soufre (métabolisme), Dispositifs électroniques portables (MeSH), Fluorescence (MeSH), Humains (MeSH), Maladies de la bouche (diagnostic), Maladies de la bouche (métabolisme), Nylons (composition chimique), Oxyde de zinc (composition chimique), Phénomènes optiques (MeSH), Polydiméthylsiloxanes (composition chimique), Protecteurs buccaux (MeSH), Volatilisation (MeSH).
- MESH :
- analyse : Composés du soufre.
- composition chimique : Composés du soufre, Nylons, Oxyde de zinc, Polydiméthylsiloxanes.
- diagnostic : Maladies de la bouche.
- métabolisme : Composés du soufre, Maladies de la bouche.
- Dispositifs électroniques portables, Fluorescence, Humains, Phénomènes optiques, Protecteurs buccaux, Volatilisation.
English descriptors
- KwdEn :
- Dimethylpolysiloxanes (chemistry), Fluorescence (MeSH), Humans (MeSH), Mouth Diseases (diagnosis), Mouth Diseases (metabolism), Mouth Protectors (MeSH), Nylons (chemistry), Optical Phenomena (MeSH), Sulfur Compounds (analysis), Sulfur Compounds (chemistry), Sulfur Compounds (metabolism), Volatilization (MeSH), Wearable Electronic Devices (MeSH), Zinc Oxide (chemistry).
- MESH :
- chemical , analysis : Sulfur Compounds.
- chemical , chemistry : Dimethylpolysiloxanes, Nylons, Sulfur Compounds, Zinc Oxide.
- diagnosis : Mouth Diseases.
- metabolism : Mouth Diseases, Sulfur Compounds.
- Fluorescence, Humans, Mouth Protectors, Optical Phenomena, Volatilization, Wearable Electronic Devices.
Abstract
Accurate detection and early diagnosis of oral diseases such as dental caries and periodontitis, can be potentially achieved by detecting the secretion of volatile sulfur compounds (VSCs) in oral cavities. Current diagnostic approaches for VSCs can detect the existence and concentrations, yet are not capable of locating the dental lesion sites. Herein, the development of a unique approach for accurately locating dental lesion sites using a fluorescent mouthguard consisting of the zinc oxide-poly(dimethylsiloxane) (ZnO-PDMS) nanocomposite to detect the local release of VSCs is reported. The ZnO-PDMS mouthguard displays a highly sensitive and selective response to VSCs, and exhibits high fluorescent stability, good biocompatibility, and low biological toxicity in normal physiological environments. Then, the wearable ZnO-PDMS mouthguard is demonstrated to be able to identify the precise locations of lesion sites in human subjects. Combined with image analysis, the mouthguards successfully uncover the precise locations of dental caries, allowing convenient screening of hidden dental lesion sites that are oftentimes omitted by dentists. Due to low cost, long-term stability, and good patient compliance, the proposed wearable mouthguard is suitable for large-scale production and enables widely applicable, preliminary yet accurate screening of dental lesions prior to dental clinics and routine physical examinations.
DOI: 10.1002/adma.202000060
PubMed: 32240566
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Quanying" sort="Fu, Quanying" uniqKey="Fu Q" first="Quanying" last="Fu">Quanying Fu</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation></author><author><name sortKey="Zhou, Cuiping" sort="Zhou, Cuiping" uniqKey="Zhou C" first="Cuiping" last="Zhou">Cuiping Zhou</name><affiliation wicri:level="1"><nlm:affiliation>Department of Emergency, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.</nlm:affiliation><country xml:lang="fr">République populaire de 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Localization of Hidden Dental Lesion Sites.</title><author><name sortKey="Li, Xuemeng" sort="Li, Xuemeng" uniqKey="Li X" first="Xuemeng" last="Li">Xuemeng Li</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation></author><author><name sortKey="Luo, Chongdai" sort="Luo, Chongdai" uniqKey="Luo C" first="Chongdai" last="Luo">Chongdai Luo</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Stomatology, Guangzhou Women and Children's Medical Center, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Stomatology, Guangzhou Women and Children's Medical Center, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation></author><author><name sortKey="Fu, Quanying" sort="Fu, Quanying" uniqKey="Fu Q" first="Quanying" last="Fu">Quanying Fu</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation></author><author><name sortKey="Zhou, Cuiping" sort="Zhou, Cuiping" uniqKey="Zhou C" first="Cuiping" last="Zhou">Cuiping Zhou</name><affiliation wicri:level="1"><nlm:affiliation>Department of Emergency, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Emergency, Nanfang Hospital, Southern Medical University, Guangzhou, 510515</wicri:regionArea><wicri:noRegion>510515</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139</wicri:regionArea><wicri:noRegion>02139</wicri:noRegion></affiliation></author><author><name sortKey="Ruelas, Marina" sort="Ruelas, Marina" uniqKey="Ruelas M" first="Marina" last="Ruelas">Marina Ruelas</name><affiliation wicri:level="1"><nlm:affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139</wicri:regionArea><wicri:noRegion>02139</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Yingshuting" sort="Wang, Yingshuting" uniqKey="Wang Y" first="Yingshuting" last="Wang">Yingshuting Wang</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation></author><author><name sortKey="He, Jinxu" sort="He, Jinxu" uniqKey="He J" first="Jinxu" last="He">Jinxu He</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Yangyang" sort="Wang, Yangyang" uniqKey="Wang Y" first="Yangyang" last="Wang">Yangyang Wang</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Yu Shrike" sort="Zhang, Yu Shrike" uniqKey="Zhang Y" first="Yu Shrike" last="Zhang">Yu Shrike Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139</wicri:regionArea><wicri:noRegion>02139</wicri:noRegion></affiliation></author><author><name sortKey="Zhou, Jianhua" sort="Zhou, Jianhua" uniqKey="Zhou J" first="Jianhua" last="Zhou">Jianhua Zhou</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275</wicri:regionArea><wicri:noRegion>510275</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139</wicri:regionArea><wicri:noRegion>02139</wicri:noRegion></affiliation></author></analytic><series><title level="j">Advanced materials (Deerfield Beach, Fla.)</title><idno type="eISSN">1521-4095</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dimethylpolysiloxanes (chemistry)</term><term>Fluorescence (MeSH)</term><term>Humans (MeSH)</term><term>Mouth Diseases (diagnosis)</term><term>Mouth Diseases (metabolism)</term><term>Mouth Protectors (MeSH)</term><term>Nylons (chemistry)</term><term>Optical Phenomena (MeSH)</term><term>Sulfur Compounds (analysis)</term><term>Sulfur Compounds (chemistry)</term><term>Sulfur Compounds (metabolism)</term><term>Volatilization (MeSH)</term><term>Wearable Electronic Devices (MeSH)</term><term>Zinc Oxide (chemistry)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Composés du soufre (analyse)</term><term>Composés du soufre (composition chimique)</term><term>Composés du soufre (métabolisme)</term><term>Dispositifs électroniques portables (MeSH)</term><term>Fluorescence (MeSH)</term><term>Humains (MeSH)</term><term>Maladies de la bouche (diagnostic)</term><term>Maladies de la bouche (métabolisme)</term><term>Nylons (composition chimique)</term><term>Oxyde de zinc (composition chimique)</term><term>Phénomènes optiques (MeSH)</term><term>Polydiméthylsiloxanes (composition chimique)</term><term>Protecteurs buccaux (MeSH)</term><term>Volatilisation (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Sulfur Compounds</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Dimethylpolysiloxanes</term><term>Nylons</term><term>Sulfur Compounds</term><term>Zinc Oxide</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Composés du soufre</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Composés du soufre</term><term>Nylons</term><term>Oxyde de zinc</term><term>Polydiméthylsiloxanes</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Mouth Diseases</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Maladies de la bouche</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Mouth Diseases</term><term>Sulfur Compounds</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Composés du soufre</term><term>Maladies de la bouche</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Fluorescence</term><term>Humans</term><term>Mouth Protectors</term><term>Optical Phenomena</term><term>Volatilization</term><term>Wearable Electronic Devices</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Dispositifs électroniques portables</term><term>Fluorescence</term><term>Humains</term><term>Phénomènes optiques</term><term>Protecteurs buccaux</term><term>Volatilisation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Accurate detection and early diagnosis of oral diseases such as dental caries and periodontitis, can be potentially achieved by detecting the secretion of volatile sulfur compounds (VSCs) in oral cavities. Current diagnostic approaches for VSCs can detect the existence and concentrations, yet are not capable of locating the dental lesion sites. Herein, the development of a unique approach for accurately locating dental lesion sites using a fluorescent mouthguard consisting of the zinc oxide-poly(dimethylsiloxane) (ZnO-PDMS) nanocomposite to detect the local release of VSCs is reported. The ZnO-PDMS mouthguard displays a highly sensitive and selective response to VSCs, and exhibits high fluorescent stability, good biocompatibility, and low biological toxicity in normal physiological environments. Then, the wearable ZnO-PDMS mouthguard is demonstrated to be able to identify the precise locations of lesion sites in human subjects. Combined with image analysis, the mouthguards successfully uncover the precise locations of dental caries, allowing convenient screening of hidden dental lesion sites that are oftentimes omitted by dentists. Due to low cost, long-term stability, and good patient compliance, the proposed wearable mouthguard is suitable for large-scale production and enables widely applicable, preliminary yet accurate screening of dental lesions prior to dental clinics and routine physical examinations.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32240566</PMID><DateCompleted><Year>2021</Year><Month>02</Month><Day>25</Day></DateCompleted><DateRevised><Year>2021</Year><Month>02</Month><Day>25</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1521-4095</ISSN><JournalIssue CitedMedium="Internet"><Volume>32</Volume><Issue>21</Issue><PubDate><Year>2020</Year><Month>May</Month></PubDate></JournalIssue><Title>Advanced materials (Deerfield Beach, Fla.)</Title><ISOAbbreviation>Adv Mater</ISOAbbreviation></Journal><ArticleTitle>A Transparent, Wearable Fluorescent Mouthguard for High-Sensitive Visualization and Accurate Localization of Hidden Dental Lesion Sites.</ArticleTitle><Pagination><MedlinePgn>e2000060</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/adma.202000060</ELocationID><Abstract><AbstractText>Accurate detection and early diagnosis of oral diseases such as dental caries and periodontitis, can be potentially achieved by detecting the secretion of volatile sulfur compounds (VSCs) in oral cavities. Current diagnostic approaches for VSCs can detect the existence and concentrations, yet are not capable of locating the dental lesion sites. Herein, the development of a unique approach for accurately locating dental lesion sites using a fluorescent mouthguard consisting of the zinc oxide-poly(dimethylsiloxane) (ZnO-PDMS) nanocomposite to detect the local release of VSCs is reported. The ZnO-PDMS mouthguard displays a highly sensitive and selective response to VSCs, and exhibits high fluorescent stability, good biocompatibility, and low biological toxicity in normal physiological environments. Then, the wearable ZnO-PDMS mouthguard is demonstrated to be able to identify the precise locations of lesion sites in human subjects. Combined with image analysis, the mouthguards successfully uncover the precise locations of dental caries, allowing convenient screening of hidden dental lesion sites that are oftentimes omitted by dentists. Due to low cost, long-term stability, and good patient compliance, the proposed wearable mouthguard is suitable for large-scale production and enables widely applicable, preliminary yet accurate screening of dental lesions prior to dental clinics and routine physical examinations.</AbstractText><CopyrightInformation>© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Xuemeng</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luo</LastName><ForeName>Chongdai</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Stomatology, Guangzhou Women and Children's Medical Center, Guangzhou, 510275, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fu</LastName><ForeName>Quanying</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Cuiping</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Emergency, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ruelas</LastName><ForeName>Marina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yingshuting</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>He</LastName><ForeName>Jinxu</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yangyang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Yu Shrike</ForeName><Initials>YS</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-0045-0808</Identifier><AffiliationInfo><Affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Jianhua</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou, 510275, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>21775168</GrantID><Agency>National Natural Science Foundation of China</Agency><Country></Country></Grant><Grant><GrantID>2017YFE0102400</GrantID><Agency>National Key R&D Program of China</Agency><Country></Country></Grant><Grant><GrantID>JCYJ20180307155036127</GrantID><Agency>Shenzhen Research Funding Program</Agency><Country></Country></Grant><Grant><GrantID>191gpy211</GrantID><Agency>youth cultivation project for college basic scientific research in 2019</Agency><Country></Country></Grant><Grant><GrantID>2017YFE0102400</GrantID><Agency>National Basic Research Program of China (973 Program)</Agency><Country></Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Adv Mater</MedlineTA><NlmUniqueID>9885358</NlmUniqueID><ISSNLinking>0935-9648</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D004129">Dimethylpolysiloxanes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009757">Nylons</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013457">Sulfur Compounds</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C085707">poly(dimethylsiloxane)-polyamide copolymer</NameOfSubstance></Chemical><Chemical><RegistryNumber>SOI2LOH54Z</RegistryNumber><NameOfSubstance UI="D015034">Zinc Oxide</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D004129" MajorTopicYN="N">Dimethylpolysiloxanes</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005453" MajorTopicYN="Y">Fluorescence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009059" MajorTopicYN="N">Mouth Diseases</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009064" MajorTopicYN="Y">Mouth Protectors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009757" MajorTopicYN="N">Nylons</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055620" MajorTopicYN="Y">Optical Phenomena</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013457" MajorTopicYN="N">Sulfur Compounds</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014835" MajorTopicYN="N">Volatilization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000076251" MajorTopicYN="Y">Wearable Electronic Devices</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015034" MajorTopicYN="N">Zinc Oxide</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">dental caries</Keyword><Keyword MajorTopicYN="N">dental mouthguards</Keyword><Keyword MajorTopicYN="N">fluorescent nanocomposites</Keyword><Keyword MajorTopicYN="N">periodontitis</Keyword><Keyword MajorTopicYN="N">volatile sulfur compounds</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>01</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>02</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>03</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>4</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>2</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32240566</ArticleId><ArticleId 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Sci. 1993, 694, 234.</Citation></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Li, Xuemeng" sort="Li, Xuemeng" uniqKey="Li X" first="Xuemeng" last="Li">Xuemeng Li</name></noRegion><name sortKey="Fu, Quanying" sort="Fu, Quanying" uniqKey="Fu Q" first="Quanying" last="Fu">Quanying Fu</name><name sortKey="He, Jinxu" sort="He, Jinxu" uniqKey="He J" first="Jinxu" last="He">Jinxu He</name><name sortKey="Luo, Chongdai" sort="Luo, Chongdai" uniqKey="Luo C" first="Chongdai" last="Luo">Chongdai Luo</name><name sortKey="Luo, Chongdai" sort="Luo, Chongdai" uniqKey="Luo C" first="Chongdai" last="Luo">Chongdai Luo</name><name sortKey="Wang, Yangyang" sort="Wang, Yangyang" uniqKey="Wang Y" first="Yangyang" last="Wang">Yangyang Wang</name><name sortKey="Wang, Yingshuting" sort="Wang, Yingshuting" uniqKey="Wang Y" first="Yingshuting" last="Wang">Yingshuting Wang</name><name sortKey="Zhou, Cuiping" sort="Zhou, Cuiping" uniqKey="Zhou C" first="Cuiping" last="Zhou">Cuiping Zhou</name><name sortKey="Zhou, Jianhua" sort="Zhou, Jianhua" uniqKey="Zhou J" first="Jianhua" last="Zhou">Jianhua Zhou</name></country><country name="États-Unis"><noRegion><name sortKey="Zhou, Cuiping" sort="Zhou, Cuiping" uniqKey="Zhou C" first="Cuiping" last="Zhou">Cuiping Zhou</name></noRegion><name sortKey="Ruelas, Marina" sort="Ruelas, Marina" uniqKey="Ruelas M" first="Marina" last="Ruelas">Marina Ruelas</name><name sortKey="Zhang, Yu Shrike" sort="Zhang, Yu Shrike" uniqKey="Zhang Y" first="Yu Shrike" last="Zhang">Yu Shrike Zhang</name><name sortKey="Zhou, Jianhua" sort="Zhou, Jianhua" uniqKey="Zhou J" first="Jianhua" last="Zhou">Jianhua Zhou</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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